Key result
Primary cardiac sarcoma uniquely presents as progressive neurologic dysfunction from brain metastases without preceding cardiac symptoms.
Why the study?
Central nervous system metastases as the initial presentation of primary cardiac sarcoma are very rare and not well characterized.
Case Report (n=1)
Highlights a rare presentation of primary cardiac sarcoma manifesting as progressive neurologic dysfunction from brain metastases prior to any cardiac symptoms.
Neurologic presentation may precede cardiac symptoms in primary cardiac sarcoma; hypothesis-generating for targeted cardiac imaging in select brain metastasis cases.
Central nervous system metastases as the presentation of primary cardiac sarcoma are a very rare entity, with only a few previously reported cases. Sarcomas specifically make up 10 to 20% of all primary cardiac tumors. Patients with primary cardiac tumors typically present with cardiac symptomatology that may include arrhythmias, obstruction to blood flow and valve function, or symptoms of heart failure. We report a unique case of a patient with a primary cardiac sarcoma who presented with progressive neurologic dysfunction secondary to brain metastases without any preceding cardiac symptoms. We describe our novel management of these unique cases and discuss the current medical and surgical approaches to treating neurologic metastases from cardiac sarcoma.
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Pasalic et al. (2013) conducted a case report in Primary cardiac sarcoma with brain metastases (n=1). Medical and surgical management was evaluated. A patient with primary cardiac sarcoma presented uniquely with progressive neurologic dysfunction from brain metastases without preceding cardiac symptoms.
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