Key result
Resecting brain metastases from primary cardiac histiocytoma improves symptoms despite fatal recurrence at 3 months.
Why the study?
Malignant fibrous histiocytoma of the heart metastasizing to the brain is extremely rare, with only one prior reported case.
Case Report (n=1)
This case report highlights a rare presentation of malignant fibrous histiocytoma of the heart metastasizing to the brain, where surgical resection provided symptomatic relief but did not prevent rapid fatal cardiac recurrence.
May offer symptomatic palliation for brain metastases from cardiac malignant fibrous histiocytoma; leaves open effective systemic strategies.
This is the second reported case of a malignant fibrous histiocytoma of the heart that metastasized to the brain. A 33-year-old woman developed headache, nausea, and ataxic gait 9 months after removal of the tumor from the left atrium of the heart. Computed tomographic and magnetic resonance imaging scans disclosed multiple metastatic tumors in the brain. Although dramatic improvement in her symptoms and signs followed the removal of the brain tumors, she died of tumor recurrence in the left atrium 3 months after the removal of the metastatic brain tumors.
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Itoyama et al. (1990) conducted a case report in Malignant fibrous histiocytoma of the heart with brain metastasis (n=1). Removal of metastatic brain tumors was evaluated on Clinical course and survival. Surgical removal of metastatic brain tumors from a primary cardiac malignant fibrous histiocytoma provided dramatic symptomatic improvement, though the patient died of local recurrence 3 months later.
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