Key result
Patients with unexplained arrhythmic symptoms show a ~7% prevalence of Brugada sign.
Why the study?
The prevalence of Brugada sign and syndrome in patients presenting with arrhythmic symptoms in Singapore was unknown.
Cross-Sectional (n=392)
No
The prevalence of Brugada sign and syndrome is high among patients presenting with unexplained arrhythmic symptoms in Singapore.
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High Brugada sign (7.1%) and syndrome (3.1%) prevalence in symptomatic Singapore patients supports targeted ECG review; leaves open true population burden pending broader studies.
Sidik et al. (2009) conducted a cross-sectional in Arrhythmic symptoms without a known cause (n=392). Unexplained pre-syncope, syncope, or palpitations was evaluated on Prevalence of Brugada sign (95% CI 4.8-10.2). Among patients presenting with unexplained arrhythmic symptoms at a Singapore clinic, the prevalence of Brugada sign was 7.1% (95% CI 4.8-10.2) and Brugada syndrome was 3.1% (95% CI 1.6-5.3).
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