Key result
Georgian MoCA outperforms MMSE in detecting aMCI and AD.
Why the study?
No Georgian language version of the Montreal Cognitive Assessment (MoCA) existed to evaluate mild cognitive impairment and Alzheimer's disease.
Does the Georgian version of MoCA improve diagnostic accuracy for aMCI and AD compared to MMSE in a Georgian-speaking population?
Cross-Sectional (n=86)
Does the Georgian version of MoCA improve diagnostic accuracy for aMCI and AD compared to MMSE in a Georgian-speaking population?
p-value: p=0.04
The Georgian version of the MoCA is a valid and sensitive screening tool for detecting aMCI and AD, demonstrating superior diagnostic accuracy compared to the MMSE.
Supports Georgian MoCA validation for aMCI/AD screening; leaves open prospective confirmation before routine use.
Montreal Cognitive Assessment (MoCA) test has been shown to be a reliable tool to detect mild cognitive impairment (MCI), however, no Georgian language version exists. The goal of this study is to determine the validity, reliability, and accuracy of Georgian version of MoCA in the evaluation of amnestic MCI (aMCI) and Alzheimer's disease (AD). Montreal Cognitive Assessment was translated into Georgian language and was administered to healthy participants (HP) and patients with aMCI and AD. We studied 46 HS, 20 patients with aMCI, and 20 patients with AD. There was significant difference in MoCA scores between HP, patients with aMCI, and patients with AD ( P = 0.04). The area under the receiver operating characteristic curve for the aMCI and AD groups by MoCA was 0.88 and 0.95, respectively, compared to 0.43 and 0.67 by Mini-Mental State Examination (MMSE). The Georgian version of MoCA is a valid, reliable, and sensitive screening tool to detect aMCI and AD in Georgian-speaking population and is superior to MMSE.
No takes yet. Share an insight, caveat, or question.
Janelidze et al. (2016) conducted a cross-sectional in Amnestic mild cognitive impairment (aMCI) and Alzheimer's disease (AD) (n=86). Georgian version of Montreal Cognitive Assessment (MoCA) vs. Mini-Mental State Examination (MMSE) was evaluated on Area under the receiver operating characteristic curve (AUC) for aMCI and AD (p=0.04). The Georgian version of MoCA accurately detected amnestic mild cognitive impairment (AUC 0.88) and Alzheimer's disease (AUC 0.95), outperforming the MMSE (AUC 0.43 and 0.67, respectively).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: