Key result
DCM patients show ~54% lower left atrial systolic strain compared to healthy controls.
Why the study?
Existing methods for assessing left atrial function have limitations including angle dependence and distortion, prompting evaluation using speckle tracking echocardiography in ischemic and non-ischemic dilated cardiomyopathy.
Does speckle-tracking echocardiography detect differences in left atrial function between patients with ischemic versus non-ischemic dilated cardiomyopathy and healthy controls?
Population
52 patients with systolic heart failure (27 IDCM, 25 NIDCM) and 15 healthy controls
Comparison
IDCM vs NIDCM vs healthy controls
Authors
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Speckle-tracking may identify impaired left atrial function in dilated cardiomyopathy; leaves open clinical utility and ischemic versus non-ischemic differentiation.
Observational (n=67)
Does speckle-tracking echocardiography detect differences in left atrial function between patients with ischemic versus non-ischemic dilated cardiomyopathy and healthy controls?
Absolute Event Rate: 28.22% vs 60.87%
p-value: p=<0.001
Speckle-tracking echocardiography is a promising tool to evaluate left atrial function and can differentiate non-ischemic from ischemic dilated cardiomyopathy based on greater impairment in reservoir and booster pump functions.
Abdelkarim et al. (2020) conducted an observational in Dilated cardiomyopathy (n=67). Dilated cardiomyopathy vs. Healthy controls was evaluated on Left atrial systolic strain (p=<0.001). Patients with dilated cardiomyopathy had significantly lower left atrial systolic strain compared to healthy controls (28.22% vs 60.87%; p<0.001) as assessed by speckle-tracking echocardiography.
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