Key result
Admission hyperglycemia predicts in-hospital MACE in elderly STEMI patients undergoing primary PCI.
Why the study?
Admission hyperglycemia in acute myocardial infarction is related to increased in-hospital and long term mortality and major cardiac adverse events, but its impact in elderly STEMI patients after primary PCI needed investigation.
Does high admission blood glucose increase mortality and major adverse cardiac events in elderly patients with STEMI treated by primary PCI?
Population
677 consecutive elderly patients (> 65 years, mean age 72.2 ± 5.4) with STEMI treated by primary PCI
Comparison
High admission blood glucose (> 168 mg/dL) vs low admission blood glucose (< 168 mg/dL)
Design
Retrospective cohort study
Follow-up
In-hospital and long term
Authors
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May support glucose for risk stratification in elderly STEMI; leaves open whether targeting it improves in-hospital outcomes.
Cohort (n=677)
Does high admission blood glucose increase mortality and major adverse cardiac events in elderly patients with STEMI treated by primary PCI?
p-value: p=< 0.001
Admission hyperglycemia is an independent predictor of in-hospital major adverse cardiac events and mortality in elderly STEMI patients undergoing primary PCI.
Ekmekçi et al. (2013) conducted a cohort in ST elevation myocardial infarction (n=677). Admission hyperglycemia (blood glucose > 168 mg/dL) vs. Low glucose group (blood glucose < 168 mg/dL) was evaluated on In-hospital major adverse cardiac events and in-hospital and long term mortality (p=< 0.001). Admission hyperglycemia (> 168 mg/dL) in elderly patients with STEMI undergoing primary PCI was an independent predictor of in-hospital major adverse cardiac events (P < 0.001).
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