Key result
Echo-derived systemic RV GPLS shows no correlation with MRI RVEF in D-TGA.
Why the study?
Echocardiographic assessment of systemic right ventricular function in patients with D-TGA post atrial switch is subjective and lacks accurate quantitative measures compared to MRI RVEF, the gold standard.
Does global peak longitudinal strain measured by speckle tracking echocardiography correlate with MRI RVEF in patients with D-TGA status post atrial switch?
Observational (n=27)
No
Does global peak longitudinal strain measured by speckle tracking echocardiography correlate with MRI RVEF in patients with D-TGA status post atrial switch?
p-value: p=0.844
The study aims to evaluate if speckle tracking echocardiography correlates with cardiac MRI for assessing systemic right ventricular function in patients with D-TGA post atrial switch.
Echocardiography-derived strain does not correlate with MRI RVEF in D-TGA systemic RV; leaves open its role versus MRI for function assessment.
Background Patients with d-transposition of the great arteries (D-TGA), status post atrial switch, are at risk for developing systemic right ventricular (RV) dysfunction. Echocardiographic (Echo) assessment of RV function is subjective because complex RV geometry does not allow accurate determination of ejection fraction (EF). RVEF measured by cardiac magnetic resonance imaging (MRI) is the gold standard for quantitative assessment of systemic RV function. New Echo measures of ventricular deformation allow for quantitative assessment of RV function. The primary aim was to explore the correlation of global peak longitudinal strain (GPLS) of the systemic RV with MRI RVEF for patients with D-TGA status post atrial switch. The secondary aim was to characterize MRI and clinical findings in this population.
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Masterson et al. (2016) conducted an observational in d-transposition of the great arteries (D-TGA) status post atrial switch (n=27). Speckle tracking echocardiography (global peak longitudinal strain) vs. Cardiac magnetic resonance imaging (MRI RVEF) was evaluated on Correlation of global peak longitudinal strain (GPLS) of the systemic RV with MRI RVEF (p=0.844). In adult patients with D-TGA status post atrial switch, echocardiography-derived global peak longitudinal strain of the systemic right ventricle did not significantly correlate with MRI right ventricular ejection fraction (p=0.844).
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