Key result
RVOT ablation with dobutamine and atropine linked to stress cardiomyopathy in a case report.
Why the study?
Stress cardiomyopathy can occur following radiofrequency ablation in the right ventricular outflow tract, but its mechanisms and clinical context are not well characterized.
Case Report (n=1)
Radiofrequency ablation in the right ventricular outflow tract, along with dobutamine and atropine, can induce a hyperadrenergic state leading to stress cardiomyopathy (Tako-Tsubo).
Vigilance for Takotsubo cardiomyopathy warranted during RVOT ablation; hypothesis-generating and requires confirmation in larger series.
A 44-year-old female undergoing radiofrequency ablation in the right ventricular outflow tract for symptomatic, frequent premature ventricular contractions developed stress cardiomyopathy (Tako-Tsubo). Stress cardiomyopathy was probably due to hyperadrenergic state induced by the procedure itself, dobutamine infusion, sympathetic nerve stimulation at the ablation site, and parasympathetic withdrawal with atropine administration.
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Hasdemir et al. (2008) conducted a case report in Symptomatic, frequent premature ventricular contractions (n=1). Radiofrequency ablation in the right ventricular outflow tract was evaluated on Development of stress cardiomyopathy (Tako-Tsubo). Radiofrequency ablation in the right ventricular outflow tract, along with dobutamine and atropine administration, induced stress cardiomyopathy (Tako-Tsubo) in a 44-year-old female.
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