Left atrial radiofrequency catheter ablation may be complicated by Tako-tsubo cardiomyopathy, potentially due to damage to autonomic ganglionated plexi leading to enhanced sympathetic tone.
Tako-tsubo cardiomyopathy may complicate left atrial ablation; case reports leave open incidence, mechanisms, and need for prospective data.
Two female patients undergoing left atrial radiofrequency catheter ablation developed Tako-tsubo cardiomyopathy. This reversible form of left ventricular dysfunction is known to occur under conditions associated with marked sympathetic nervous activation. Radiofrequency catheter ablation in the left atrium can damage autonomic ganglionated plexi, leading to vagal withdrawal, thus resulting in enhanced sympathetic tone. Tako-tsubo cardiomyopathy has not been previously described following radiofrequency catheter ablation.
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Derntl et al. (2007) studied this question.
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