The present study was aimed to know the heamatological alteration due to imidacloprid and spinosad (neonicotinoid and bacterial insecticide respectively) and their amelioration with vitamin E and silymarin in male Cobb broiler chicken. The experiment was carried out for 28 days. Group 1 served as control, group 2 treated with imidacloprid @ 50 ppm in feed, group 3 was treated with spinosad @ 1000 ppm in feed, group 4 was treated with imidacloprid @ 50 ppm and spinosad @ 1000 ppm in feed, group 5 was treated with imidacloprid @ 50 ppm, spinosad @ 1000 ppm and Vitamin E @ 20 ppm in feed and group 6 was treated with imidacloprid @ 50 ppm, spinosad @ 1000 ppm and silymarin @ 1000 ppm in feed. The weekly body weight gains were significantly (P < 0.05) decreased in groups 2, 3 and 4, 5 and 6. Haematological observations revealed a significant (P < 0.05) decrease in overall means of TEC, Hb concentration, MCV, MCH, MCHC and PCV except TLC in groups 2, 3 and 4, 5 and 6 in which there is a significant (P < 0.05) increase. These results revealed that exposure of imidacloprid, spinosad and its combination resulted in alterations in haematological parameters.
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Lakshman et al. (2017) studied this question.
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