Key result
Echocardiography systematically underestimates LAV and RAV versus MDCT, with less bias for LAV.
Why the study?
To compare left and right atrial volumes measured by 2-D and 3-D echocardiography with those determined by ECG-gated multidetector CT in healthy dogs.
Does 2-D and 3-D echocardiography accurately measure left and right atrial volumes compared to MDCT in healthy dogs?
Observational (n=11)
Does 2-D and 3-D echocardiography accurately measure left and right atrial volumes compared to MDCT in healthy dogs?
Echocardiography may be an acceptable alternative to MDCT for measuring left atrial volume, but not right atrial volume, in dogs.
Echocardiography may suffice for left but not right atrial volumes in healthy dogs; leaves open validation in disease or clinical use.
OBJECTIVE: To compare left atrial volume (LAV) and right atrial volume (RAV) determined by 2-D and 3-D echocardiographic methods with the LAV and RAV determined by ECG-gated multidetector CT (MDCT) for healthy dogs. ANIMALS: 11 healthy purpose-bred young adult hound-type dogs. PROCEDURES: Each dog was anesthetized and underwent MDCT and a complete echocardiographic examination. Modality-specific software was used to measure the respective atrial volumes at ventricular end systole, and LAV and RAV measurements were subsequently indexed to body weight and compared among imaging modalities. RESULTS: The LAV determined by echocardiographic methods did not differ significantly from the LAV determined by MDCT. However, the RAV determined by 3-D echocardiography and 2-D echocardiography via the left apical and left cranial windows differed significantly from the RAV determined by MDCT. Bland-Altman analyses indicated that the indexed LAV and RAV determined by echocardiographic methods were systematically underestimated, compared with MDCT measurements, but the bias was much smaller for LAV than for RAV. CONCLUSIONS AND CLINICAL RELEVANCE: Results suggested that, for dogs, echocardiography might be an acceptable alternative to MDCT for measurement of LAV but not for measurement of RAV. However, the study population was small and homogenous in terms of breed, age, and weight. These findings need to be validated in a larger, more varied population of dogs with and without cardiac disease.
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Owens et al. (2019) conducted an observational in Healthy dogs (n=11). 2-D and 3-D echocardiography vs. ECG-gated multidetector CT (MDCT) was evaluated on Left atrial volume (LAV) and right atrial volume (RAV). Echocardiographic methods systematically underestimated indexed left and right atrial volumes compared with MDCT, though bias was smaller for left atrial volume.
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