Key result
Chaphamaparvovirus galliform shows no association with enteritis cases in broiler and turkey flocks.
Why the study?
Chaphamaparvovirus galliform has been newly reported across species, but its detection and genetic characterization in broiler and turkey flocks in Türkiye were not previously described.
Observational (n=1,060)
Yes
p-value: p=0.617
This study reports the first detection and molecular characterization of Chaphamaparvovirus galliform in turkey and broiler flocks in Türkiye, finding no significant association with enteritis.
GaChpV detection without enteritis link cautions against causal attribution in poultry; extends geographic data but leaves pathogenicity open.
BACKGROUND: A newly uncovered parvovirus, Chaphamaparvovirus, continues to be reported across various species. This study investigated the detection and genetic characterization of Chaphamaparvovirus galliform (GaChpV) in poultry, specifically broilers and turkeys, from various regions in Türkiye. To address this, comprehensive sampling and analysis were conducted to better understand the virus's distribution and impact in these avian populations. RESULTS: In 2023, a total of 1060 fecal samples were collected from 76 broiler flocks (10 healthy and 66 with enteritis) and 30 turkey flocks (10 healthy and 20 with enteritis). Using nested PCR with specific primer sets, the study detected GaChpV in 36 out of 76 broiler flocks (47.3%) and 2 out of 30 turkey flocks (6,6%). Although GaChpV was detected at notable frequencies, the analysis revealed no statistically significant association between GaChpV and enteritis cases (p = 0.617). In this study, the nucleotide sequences (nt) of the capsid genes from GaChpV strains isolated from broilers and turkeys were 99 to 100% identical. Furthermore, these strains exhibited a high degree of genetic similarity ranging from 73 to 98% to Chaphamaparvovirus galliform 2 (GaChpV-2) strains from Europe, China, and Brazil. Complete genome sequencing of a broiler strain (CkChPV/2023/UN-2-TR) yielded a genome of 4,229 nucleotides, with sequence identity ranging from 78.93 to 98.82% compared to other GaChpV strains. Phylogenetic analysis further revealed that the CkChPV/2023/UN-2-TR strain clustered with GaChpV-2 strains, highlighting its genetic relatedness and diversity within the GaChpV family. The study also investigated genetic recombination signals and identified potential B-cell linear epitopes, contributing to a better understanding of the virus's genetic diversity and antigenic characteristics. CONCLUSIONS: This report represents the first detection of GaChpV in turkey and broiler flocks in Türkiye. Notably, research on this topic in turkeys is quite limited. The data derived from this study will contribute to elucidating the molecular epidemiology and evolutionary dynamics of GaChpV.
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Aslan et al. (2025) conducted an observational in Chaphamaparvovirus galliform (GaChpV) infection (n=1,060). Chaphamaparvovirus galliform (GaChpV) was evaluated on Association between GaChpV and enteritis cases (p=0.617). Chaphamaparvovirus galliform was detected in 47.3% of broiler and 6.6% of turkey flocks in Türkiye, with no significant association between the virus and enteritis cases (p=0.617).
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