Key result
Non-invasive methods can assess peripheral vascular and endothelial dysfunction in PAH.
Why the study?
Pulmonary endothelial dysfunction in PAH involves systemic vascular derangement, but non-invasive methods to assess peripheral endothelial function have recently gained interest.
Population
Individuals with pulmonary arterial hypertension
Comparison
Non-invasive assessment methods of endothelial function and microcirculation
Design
Review of current evidence
Authors
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May aid non-invasive endothelial assessment in PAH; leaves open clinical adoption pending prospective validation.
Non-invasive methods such as plethysmography, nailfold videocapillaroscopy, and imaging techniques can effectively assess systemic endothelial dysfunction and microcirculation derangement in patients with pulmonary arterial hypertension.
Dara et al. (2021) conducted a review in Pulmonary Arterial Hypertension. Non-invasive assessment methods (NVC, NIRS, MRI, biomarkers) was evaluated. Non-invasive methods including nailfold videocapillaroscopy, near-infrared spectroscopy, and imaging techniques can be utilized to assess peripheral vascular function and endothelial dysfunction in PAH.
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