Key result
Age ≥85 years linked to lower odds of ACE inhibitor prescription at discharge versus ages 65-74.
Why the study?
The extent to which age influences the underutilization of ACE inhibitors in heart failure patients has not been well studied.
Does advanced age reduce the likelihood of ACE inhibitor prescription at discharge in older hospitalized heart failure patients?
Population
285 older Medicare beneficiaries with heart failure and left ventricular systolic dysfunction in Alabama
Comparison
Patients aged 85 years and older vs patients aged 65 to 74 years regarding ACE inhibitor use
Design
Observational cohort study
Authors
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Older age was associated with lower ACE inhibitor use in HF; leaves open whether age-targeted interventions improve prescribing.
Observational (n=285)
Does advanced age reduce the likelihood of ACE inhibitor prescription at discharge in older hospitalized heart failure patients?
Advanced age (≥85 years) is independently associated with lower use and initiation of ACE inhibitors in older patients hospitalized with heart failure and left ventricular systolic dysfunction.
Ahmed et al. (2002) conducted an observational in heart failure with left ventricular systolic dysfunction (n=285). Age ≥85 years vs. Age 65 to 74 years was evaluated on Prescription of ACE inhibitors at discharge. Age ≥85 years was associated with lower odds of receiving ACE inhibitors at discharge compared to ages 65-74 years, in a cohort where the overall prescription rate was 63%.
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