Key result
ECMO linked to ~80% neurologically intact survival in patients with post-partum hemorrhage.
Why the study?
The safety and applicability of extracorporeal membrane oxygenation (ECMO) in patients with post-partum hemorrhage were unclear.
Does extracorporeal membrane oxygenation improve survival in patients with severe post-partum hemorrhage?
Observational (n=5)
No
Does extracorporeal membrane oxygenation improve survival in patients with severe post-partum hemorrhage?
ECMO can be successfully utilized as a life-saving intervention in patients with severe post-partum hemorrhage, yielding high survival rates without neurological sequelae.
May support ECMO in refractory post-partum hemorrhage; hypothesis-generating and requires prospective validation before practice change.
Extracorporeal membrane oxygenation (ECMO) is commonly used in patients who experience circulatory arrest or significant cardiac dysfunction and is associated with improved clinical outcomes. We conducted a retrospective observational study on ECMO application at a single tertiary center over a five-year period. Five patients who suffered post-partum hemorrhage resulting from uterine atony were treated with ECMO. The mean age was 36.8 ± 3.9 years; the mean gestational age was 37.8 ± 2.2 weeks; the initial mean maternal hemoglobin level was 5.0 ± 2.4 mg/dL; and the mean estimated blood loss was 3260 ± 1545 mL before treatment. All patients were treated with venoarterial ECMO and one was treated with both venoarterial and venovenous ECMO. The mean ECMO usage duration was 32.6 ± 18.8 h (range 10-54). Four (80%) patients survived until discharge without experiencing neurological sequela. ECMO should not be a contraindication for treatment of post-partum hemorrhage and such patients should be weaned as soon as possible to ensure the early recovery of cardiac function.
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Huang et al. (2017) conducted an observational in Post-partum hemorrhage (n=5). Extracorporeal membrane oxygenation (ECMO) was evaluated on Survival until discharge without experiencing neurological sequela. Extracorporeal membrane oxygenation (ECMO) was associated with survival until discharge without neurological sequela in 80% (4 of 5) of patients with post-partum hemorrhage.
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