Key result
In postpartum patients with refractory shock or respiratory failure, extracorporeal membrane oxygenation resulted in an 80% survival-to-discharge rate, significantly higher than the 56% rate in similar-aged women receiving ECMO (P=0.0004).
Why the study?
Extracorporeal membrane oxygenation is increasingly utilized, but only a limited level of experience has been reported in postpartum cardiopulmonary failure.
Does extracorporeal membrane oxygenation (ECMO) improve survival-to-discharge in critically ill postpartum patients with refractory shock or respiratory failure compared to female patients of similar age receiving ECMO?
Comparison
Postpartum ECMO patients vs female patients of similar age who received ECMO
Design
Retrospective observational study
Authors
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ECMO may be feasible in select postpartum failure; leaves open optimal selection, timing, and outcomes in prospective studies.
Observational (n=10)
No
Does extracorporeal membrane oxygenation (ECMO) improve survival-to-discharge in critically ill postpartum patients with refractory shock or respiratory failure compared to female patients of similar age receiving ECMO?
Absolute Event Rate: 80% vs 56%
p-value: p=0.0004
ECMO is feasible and associated with excellent survival outcomes (80% survival-to-discharge) in postpartum patients with refractory shock or respiratory failure, despite a high risk of major bleeding.
Ko et al. (2021) conducted an observational in Postpartum refractory shock or respiratory failure (n=10). Extracorporeal membrane oxygenation (ECMO) vs. Women aged 15-44 years who received ECMO at the same institution was evaluated on Survival-to-discharge rate (p=0.0004). In postpartum patients with refractory shock or respiratory failure, extracorporeal membrane oxygenation resulted in an 80% survival-to-discharge rate, significantly higher than the 56% rate in similar-aged women receiving ECMO (P=0.0004).