Key result
Carotid dolicoarteriopathies are not linked to increased cerebrovascular events over 10 years.
Why the study?
Carotid dolicoarteriopathies are commonly detected on carotid imaging, but their potential role in the development of cerebrovascular diseases remains unclear.
Does the presence of carotid dolicoarteriopathies (CDA) increase the risk of cerebrovascular events in high-risk hypertensive patients?
Cohort (n=2,124)
Does the presence of carotid dolicoarteriopathies (CDA) increase the risk of cerebrovascular events in high-risk hypertensive patients?
Carotid dolicoarteriopathies are not associated with an increased risk of long-term cerebrovascular events in high-risk hypertensive patients.
CDA does not warrant altered cerebrovascular risk stratification in hypertensives; leaves open confirmation in larger prospective cohorts.
BACKGROUND: Carotid dolicoarteriopathies (CDA) are a common finding during the carotid ultrasound or angiography, but their potential role in the development of cerebrovascular diseases is still unclear. Aim of this study is to clarify the possible relationship between CDA and the occurrence of cerebral events. METHODS: We performed a retrospective analysis on 2124 hypertensive patients with high cardiovascular risk that underwent carotid ultrasound from January 2000 to December 2008. Follow-up data on cerebrovascular events (transient ischemic attack and/or stroke occurrence) at 10 years were collected. RESULTS: The global prevalence of CDA in the study population was 12.9% (274/2124), and carotid kinking was more frequent in females and in the left carotid axis. The percentage of cerebrovascular events among hypertensive patients with CDA was similar to those occurred in the group of patients without CDA (10.94% vs. 10.97%, P=NS), with no differences in the number of strokes (8.39% vs. 8.38% P=NS) and TIA (2.55% vs. 2.59% P=NS). CONCLUSIONS: CDA are not associated with a major occurrence of cerebrovascular events in a high-risk population of hypertensives.
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Valvano et al. (2020) conducted a cohort in Hypertension with high cardiovascular risk (n=2,124). Carotid dolicoarteriopathies (CDA) vs. Patients without CDA was evaluated on Cerebrovascular events (transient ischemic attack and/or stroke occurrence) (p=NS). Carotid dolicoarteriopathies were not associated with an increased risk of cerebrovascular events compared to patients without the condition (10.94% vs. 10.97%, P=NS) over a 10-year follow-up.
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