Key result
Both HFrEF and HFpEF are linked to decreased left atrial phasic functions compared to controls.
Why the study?
Left atrial volumes and phasic functions in heart failure patients with preserved or low ejection fractions were not fully characterized.
How do left atrial volumes and phasic functions differ between heart failure patients with preserved versus low ejection fractions and healthy controls?
Case-Control (n=89)
How do left atrial volumes and phasic functions differ between heart failure patients with preserved versus low ejection fractions and healthy controls?
p-value: p=<0.001
Left atrial phasic functions are impaired in all heart failure patients, with reservoir and pumping functions more severely affected in HFpEF and conduit function more affected in HFrEF.
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LA phasic differences may aid HF subtype differentiation; hypothesis-generating and should not yet change practice.
Emine Bilen (2012) conducted a case-control in Heart failure (n=89). Heart failure (low or preserved ejection fraction) vs. Age- and sex-matched controls without heart failure was evaluated on Left atrial phasic functions (reservoir, conduit, and pumping functions) (p=<0.001). Heart failure with low or preserved ejection fraction was associated with significantly decreased left atrial phasic functions compared to controls without heart failure (p<0.001).
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