Key result
Modulating pacemaker rate-responsive mode enables a stroke patient with severe orthostatic hypotension to sit >3 hours.
Why the study?
The impact of periodic modulation of a programmable pacemaker during stroke rehabilitation in patients with chronic atrial fibrillation and pacemaker implantation is not well described.
Case Report (n=1)
Periodic modulation of a programmable pacemaker's rate-responsive mode can improve functional outcomes during stroke rehabilitation in patients with severe orthostatic hypotension.
May support individualized rate modulation for orthostatic hypotension in stroke; hypothesis-generating and requires controlled validation before adoption.
A 65-year-old man was implanted with an artificial pacemaker for chronic bradycardic atrial fibrillation associated with hypertensive heart disease. Five years after the pacemaker implantation, he suffered from a cerebral embolism. Approximately 4.5 months after the ictus, he was transferred to the rehabilitation ward. He had flaccid left hemiplegia and severe disuse syndrome. He could not sit and could tilt his head up for only two minutes because of severe orthostatic hypotension. By modulating the rate-responsive mode of the pacemaker every 2-4 weeks, we were able to rehabilitate the patient. Thus, the patient could sit in a wheelchair for more than three hours. This case emphasizes the importance of examining the mode and function of a previously implanted artificial pacemaker. In accord with varying rehabilitation programs and gradual improvement in a patient's physical activities, periodic modulation of a programmable pacemaker can lead to a better functional outcome during rehabilitation therapy.
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Muramatsu et al. (2003) conducted a case report in Cerebral embolism and severe disuse syndrome (n=1). Periodic modulation of the rate-responsive mode of the pacemaker was evaluated on Functional outcome (ability to sit). Periodic modulation of a programmable pacemaker's rate-responsive mode enabled a 65-year-old stroke patient with severe orthostatic hypotension to sit in a wheelchair for over three hours.
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