Key result
First-in-human WiSE-CRT use provides wireless LV endocardial pacing in complete heart block with obliterated veins.
Why the study?
Wireless left ventricular endocardial pacing using the WiSE-CRT system was developed to provide CRT in patients where LV epicardial access is unobtainable.
Case Report (n=1)
Demonstrates the feasibility of wireless left ventricular endocardial pacing in a patient with complete heart block and no venous access.
Initial human data on wireless endocardial pacing supports device refinement; leaves open safety, efficacy, and indications pending prospective trials.
Left ventricular (LV) endocardial pacing using the WiSE-CRT (Wireless Stimulation Endocardially for Cardiac Resynchronization) system (EBR Systems, Sunnyvale, CA) is a novel technology that uses ultrasound energy to deliver wireless signals to pace the LV. This system was originally designed to offer a solution for patients with indicated cardiac resynchronization therapy (CRT) but in whom LV epicardial access was unobtainable.1 In this case, we present a first-in-human use of the WiSE-CRT system to pace the LV in a patient with an obliterated venous system that made it impossible to use any traditional pacing techniques.
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Hemam et al. (2022) conducted a case report in Obliterated venous system and complete heart block (n=1). WiSE-CRT system (wireless left ventricular endocardial pacing) was evaluated. First-in-human use of the WiSE-CRT system provided wireless left ventricular endocardial pacing in a patient with an obliterated venous system and complete heart block.
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