Key result
IV amiodarone elicits a response in ~80% of young patients with postoperative VT.
Why the study?
Oral amiodarone is useful for problematic arrhythmias in children but its pharmacokinetics limit use in acute settings, necessitating evaluation of intravenous amiodarone efficacy.
Population
10 patients (mean age 6.8 years) with life-threatening tachyarrhythmias
Comparison
Intravenous amiodarone after failure of standard therapies
Design
Observational study
Authors
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Clinical evaluation demonstrates acute rhythm stabilization in young patients with tachyarrhythmias, highlighting intravenous amiodarone as a crucial emergency therapy.
Observational (n=10)
Perry et al. (1993) conducted an observational in Life-threatening tachyarrhythmias (n=10). Intravenous amiodarone was evaluated on Responsiveness to intravenous amiodarone (95% CI 40-99). Intravenous amiodarone was well tolerated and elicited a response in 80% (8 of 10) of young patients with postoperative ventricular tachycardia (95% CI 40-99%).
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