AgOTf‐Catalysed Regioselective C1‐Amination of Pyrrolo[1,2‐a]quinoxaline With Azodicarboxylates

This is the authors' abstract. We don't add key points for this paper.

AgOTf‐catalysed regioselective C1‐amination of pyrrolo[1,2‐a]quinoxaline has been developed. The reaction allowed the use of various pyrrolo[1,2‐a]quinoxalines and azodicarboxylates as coupling partners to afford C1‐aminated products with good to excellent yields. The synthetic strategy showed excellent regioselectivity, functional group tolerance as well as gram‐scale synthesis. The amination products were further modified to furnish structurally diverse pyrrolo[1,2‐a]quinoxaline compounds.