Key result
Myocardial revascularization linked to reduced physical and psycho-emotional health at six months.
Why the study?
The long-term quality of life and its influencing factors after myocardial revascularisation in ACS patients during the COVID-19 pandemic were not well studied.
What is the quality of life and what factors influence it 6 months after myocardial revascularization in patients with acute coronary syndrome during the COVID-19 pandemic?
Observational (n=658)
What is the quality of life and what factors influence it 6 months after myocardial revascularization in patients with acute coronary syndrome during the COVID-19 pandemic?
p-value: p=< 0.002
Patients undergoing myocardial revascularization for ACS during the COVID-19 pandemic experience reduced physical and mental health at 6 months, exacerbated by COVID-19 infection and comorbidities.
May warrant integrated QoL surveillance after ACS revascularization; hypothesis-generating for pandemic and comorbidity effects pending prospective studies.
Aim. To study the quality of life and how it is influenced by different factors in the long term after myocardial re-vascularisation in patients with coronary artery disease who had acute coronary syndrome during the coronavirus disease 2019 (COVID-19) pandemic.Methods. We examined 658 patients with coronary artery disease and acute coronary syndrome (mean age 66.4 ± 4.3 years). Percutaneous coronary intervention (600 patients) and coronary artery bypass grafting with cardio-pulmonary bypass (58 patients) were performed. Six months after myocardial re-vascularisation, we assessed patients' quality of life using the SF-36 questionnaire. We identified factors that affect the quality of life using multivariate regression analysis.Results. After myocardial revascularisation, the patients had a reduced overall indicator of physical health (< 40 points). The overall indicator of psycho-emotional health was higher than physical (p < 0.002) but did not exceed 50 points. We noted the adverse effect of COVID-19 (regardless of disease severity) on the assessment. Also, COVID-19 was associated with increased anxiety. A history of concomitant diabetes mellitus, obesity, stroke and percutaneous coronary intervention had a negative effect on the overall indicators of physical and mental health.Conclusion. Patients with coronary artery disease who had acute coronary syndrome after myocardial re-vascularisation are characterised by reduced indicators of physical and average indicators of mental health in the long term. COVID-19, regardless of disease severity, has a negative impact on patients' general state of health, social activity and emotional background. A history of diabetes mellitus, obesity, stroke and percutaneous coronary intervention adversely affects the physical and mental health indicators. Received 4 August 2021. Revised 31 August 2021. Accepted 1 September 2021. Funding: This work was carried out within the framework of the state task of the Ministry of Health of the Russian Federation (No. 121031300225-8). Conflict of interest: Authors declare no conflict of interest. Contribution of the authorsConception and study design: O.V. Kamenskaya, V.V. LomivorotovData collection and analysis: A.S. KlinkovaStatistical analysis: A.S. KlinkovaDrafting the article: A.S. Klinkova, I.Yu. LoginovaCritical revision of the article: O.V. Kamenskaya, A.M. ChernyavskiyFinal approval of the version to be published: A.S. Klinkova, O.V. Kamenskaya, I.Yu. Loginova, A.M. Chernyavskiy, V.V. Lomivorotov
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Клинкова et al. (2021) conducted an observational in Coronary artery disease and acute coronary syndrome (n=658). COVID-19 and myocardial re-vascularisation was evaluated on Quality of life assessed by the SF-36 questionnaire (p=< 0.002). Six months after myocardial revascularisation, patients had reduced physical health (<40 points) and psycho-emotional health (<50 points, p<0.002 vs physical health).
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