Why the study?
The clinical manifestation and characteristics of cardiac calcified amorphous tumor (CAT) remain unclear despite increasing case reports.
What are the clinical characteristics of cardiac calcified amorphous tumor (CAT) and how do they differ based on the presence of end-stage renal disease (ESRD)?
Population
106 criteria-matched CAT cases from 113 articles published between 1997 and 2022
Comparison
Differences in CAT features with and without end-stage renal disease (ESRD)
Design
Narrative review with statistical analysis of clinical features
Key result
End-stage renal disease in patients with cardiac calcified amorphous tumors was associated with mobile tumors located in the mitral valve region, which increased the risk of embolism.
Authors
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May increase embolism risk in ESRD patients with mobile mitral CAT; leaves open prospective validation before guiding management.
What are the clinical characteristics of cardiac calcified amorphous tumor (CAT) and how do they differ based on the presence of end-stage renal disease (ESRD)?
Cardiac calcified amorphous tumors exhibit distinct morphological and mobility characteristics depending on the presence of end-stage renal disease, with mobile tumors in the mitral valve region posing a high risk of embolism in ESRD patients.
Takahashi et al. (2024) conducted a review in Cardiac Calcified Amorphous Tumor (n=106). End-stage renal disease (ESRD) vs. Without ESRD was evaluated on Clinical features including shape, location, mobility, and risk of embolism. End-stage renal disease in patients with cardiac calcified amorphous tumors was associated with mobile tumors located in the mitral valve region, which increased the risk of embolism.
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