Key result
Metabolic syndrome linked to ~63% higher prevalence of angiographic CAD.
Why the study?
The clinical significance of metabolic syndrome score, metabolic syndrome, and its individual components for predicting coronary artery disease risk remains unclear.
Does metabolic syndrome and its individual components predict the prevalence and severity of angiographic coronary artery disease in patients with suspected myocardial ischemia?
Population
858 participants undergoing coronary angiography for suspected myocardial ischemia
Comparison
Metabolic syndrome score, metabolic syndrome, and individual components versus absence
Design
Observational cross-sectional study
Authors
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May support CAD risk stratification; hypothesis-generating and requires prospective validation before practice change.
Observational (n=858)
Does metabolic syndrome and its individual components predict the prevalence and severity of angiographic coronary artery disease in patients with suspected myocardial ischemia?
Odds Ratio: 1.631 (95% CI 1.208–2.203)
p-value: p=0.001
Metabolic syndrome and elevated fasting glucose are independent risk factors for the prevalence of angiographic CAD, while the metabolic syndrome score and elevated fasting glucose correlate with disease severity.
Gui et al. (2017) conducted an observational in Coronary artery disease (n=858). Metabolic syndrome vs. Absence of metabolic syndrome was evaluated on Prevalence of angiographic CAD (OR 1.631, 95% CI 1.208-2.203, p=0.001). Metabolic syndrome was independently associated with the prevalence of angiographic coronary artery disease (OR 1.631; 95% CI 1.208-2.203; P=0.001).
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