Key result
Gestational diabetes is linked to markedly higher risks of obstetric and neonatal complications including macrosomia.
Why the study?
Obstetric and neonatal complications derived from gestational diabetes are prevalent and represent a significant public health problem requiring comprehensive evaluation.
Does gestational diabetes mellitus increase the risk of short-term obstetric and neonatal complications in pregnant women?
Population
527,351 pregnant women including 65,852 with gestational diabetes mellitus
Comparison
Pregnant women with gestational diabetes mellitus vs without gestational diabetes mellitus
Design
Systematic review of 13 studies
Authors
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GDM complications remain highly prevalent and clinically relevant; reinforces need for improved screening adherence in routine practice.
Systematic Review (n=527,351)
Does gestational diabetes mellitus increase the risk of short-term obstetric and neonatal complications in pregnant women?
Effect estimate: OR 1.2 to 5.2
Gestational diabetes is significantly associated with a high prevalence of short-term obstetric and neonatal complications, particularly hypoglycemia and macrosomia, highlighting the need for early screening and management.
Vargas et al. (2023) conducted a systematic review in Gestational diabetes (n=527,351). Gestational diabetes vs. No gestational diabetes was evaluated on Macrosomia (OR 1.2 to 5.2). Gestational diabetes is associated with increased risks of obstetric and neonatal complications, including macrosomia (OR 1.2 to 5.2) and hypoglycemia (OR 3.19 to 11.97).
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