Late onset epilepsy and dementia with Lewy bodies: Underestimated association?

Relationship between Alzheimer's disease (AD) and late onset epilepsy (LOE) has been widely described leading to an expansion of the clinical spectrum of AD. Dementia with Lewy bodies (DLB) has scarce data detailing its association with epilepsy. We report 4 patients presenting DLB and LOE. Most of them developed LOE before the first symptoms of DLB, they all presented Parkinsonism and cognitive fluctuations, half of them presented status epilepticus and none had co-amyloid pathology, sv2a inhibitors were poorly tolerated and routine EEG were often inefficient to diagnose epileptiform abnormalities.