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October 9, 2025Epilepsia OpenOpen Access

Late‐onset epilepsy of unknown etiology is more treatment‐responsive than acquired lesional late‐onset epilepsy

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Authors

LHL. Brian HickmanBPB. P. PandeyAFA J Fish

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Overview

Retrospective analysis reveals late-onset epilepsy of unknown etiology is more treatment-responsive, suggesting differing clinical features.

Key Points

  • Late-onset epilepsy of unknown etiology exhibited a lower seizure frequency than acquired lesional epilepsy.
  • Patients with late-onset epilepsy of unknown etiology required fewer antiseizure medications compared to acquired lesional epilepsy.
  • There was a significantly lower history of status epilepticus in the late-onset epilepsy of unknown etiology group.
  • Late-onset epilepsy of unknown etiology displayed fewer vascular comorbidities compared to its acquired counterpart.

Cite This Study

Hickman et al. (2025) studied this question.

synapsesocial.com/papers/68e80eb363e2e2f707877c0ahttps://doi.org/10.1002/epi4.70156
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