Key result
Elevated SYNTAX scores associate with ~2-fold higher 5-year mortality but lack independent predictive value.
Why the study?
The SYNTAX score is used to determine optimal myocardial revascularization strategy, but its ability to predict postoperative mortality after coronary artery bypass graft surgery was unclear.
Does the SYNTAX score predict postoperative mortality in patients undergoing coronary artery bypass grafting?
Population
1100 consecutive patients referred for coronary artery bypass graft surgery over 4 years in Bangladesh
Comparison
Intermediate (23–32) and high (≥33) SYNTAX scores vs low (≤22) SYNTAX score
Design
Cohort study
Follow-up
5 years
Authors
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Higher SYNTAX scores associate with elevated late mortality after CABG but lack independent predictive value; leaves open incremental utility beyond EuroSCORE in observational cohorts.
Cohort (n=1,100)
Does the SYNTAX score predict postoperative mortality in patients undergoing coronary artery bypass grafting?
Absolute Event Rate: 19.5% vs 9.5%
p-value: p=< 0.05
While higher SYNTAX scores are associated with increased 5-year mortality after coronary artery bypass grafting, the score is not an independent predictor of late mortality.
Ranjan et al. (2019) conducted a cohort in Complex coronary artery disease (n=1,100). Intermediate and high SYNTAX scores vs. Low SYNTAX score (≤22) was evaluated on 5-year mortality (p=< 0.05). Intermediate and high SYNTAX scores were associated with higher 5-year mortality (18.6% and 19.5%) than low scores (9.5%, p<0.05), but the score was not an independent predictor of late mortality.
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