Cardiac troponins and prediction of coronary artery disease risk

Cardiac troponins are released into the bloodstream as a result of myocardial injury and their in the blood is in routine clinical use for the diagnosis of myocardial infarction. A range of cardiac and non-cardiac conditions may also cause a rise in troponin. A number of recent have found that high-sensitivity troponin is significantly associated with future coronary in people without prior cardiovascular disease. Some studies have investigated its benefit in risk prediction models, but have been too small to show a statistically improvement in the C statistic. Nevertheless, troponin measurements should be as a cardiovascular risk marker among healthy people as well as a diagnostic marker for infarction.