Key result
General anaesthesia with epidural analgesia shows no benefit over general anaesthesia alone for peroperative blood loss.
Why the study?
The effect of epidural analgesia combined with general anaesthesia on peroperative blood loss during major abdominal surgery was uncertain compared to general anaesthesia alone.
Does general anaesthesia combined with epidural analgesia reduce peroperative blood loss in patients undergoing major abdominal surgery?
Population
97 patients undergoing major abdominal surgery including colon resection, abdominal-perineal excision, and cystectomy
Comparison
General anaesthesia combined with epidural analgesia vs general anaesthesia alone
Design
Retrospective cohort study
Authors
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No blood loss reduction with added epidural in this cohort; leaves open confirmation in randomized trials.
Cohort (n=97)
Does general anaesthesia combined with epidural analgesia reduce peroperative blood loss in patients undergoing major abdominal surgery?
The addition of epidural analgesia to general anaesthesia does not significantly reduce peroperative blood loss during major abdominal surgery.
Jensen et al. (1978) conducted a cohort in Major abdominal surgery (n=97). General anaesthesia combined with epidural analgesia vs. General anaesthesia alone was evaluated on Peroperative blood loss. General anaesthesia combined with epidural analgesia did not significantly reduce peroperative blood loss compared to general anaesthesia alone during major abdominal surgery.
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