Key result
Postoperative plasma renin activity normalization predicts ~87% long-term blood pressure control after renovascular hypertension surgery.
Why the study?
Measurement of plasma renin activity following operation for renovascular hypertension may provide a more direct and immediate assessment of operative success or failure than blood pressure alone.
Does postoperative plasma renin activity measurement predict long-term blood pressure control in patients undergoing operation for renovascular hypertension?
Population
23 patients undergoing operation for renovascular hypertension
Comparison
Preoperative and postoperative plasma renin activity levels
Design
Observational cohort study with serial PRA measurements
Follow-up
Average 29 months
Authors
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Postoperative plasma renin normalization was associated with long-term BP control after renovascular surgery; leaves open whether routine measurement should change practice.
Observational (n=23)
Does postoperative plasma renin activity measurement predict long-term blood pressure control in patients undergoing operation for renovascular hypertension?
Postoperative measurement of plasma renin activity provides an immediate assessment of operative success and predicts long-term blood pressure control in patients with renovascular hypertension.
Sewell H. Dixon (1971) conducted an observational in Renovascular hypertension (n=23). Operation for renovascular hypertension was evaluated on Normalization of plasma renin activity and blood pressure. Postoperative normalization of plasma renin activity in 20 of 23 patients undergoing surgery for renovascular hypertension predicted excellent or good long-term blood pressure control at 29 months.
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