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September 17, 2026Journal of Drug Delivery and TherapeuticsOpen Access

Advanced Nanocarriers for Cancer Therapies: Recent Developments and Clinical Challenges

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Authors

ARAliya RehmaniPRPalak Ghanshyam RahangdalePMPayal Dilip Meshram

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Overview

Review demonstrates enhanced antitumor delivery and reduced toxicity via engineered nanocarriers in oncology, highlighting translation hurdles like scalability and regulation.

Key Points

  • Evaluate recent advances in advanced nanocarrier design and delivery strategies for cancer therapy while assessing key biological, manufacturing, and regulatory barriers to clinical translation.
  • Literature review and comparative analysis of lipid-based, polymeric, inorganic, biomimetic, and hybrid nanocarrier platforms for oncology applications.
  • Evaluation of design principles, targeting mechanisms, therapeutic efficacy, biosafety considerations, manufacturing scalability, and regulatory approval pathways.
  • Lipid, polymeric, inorganic, biomimetic, and hybrid systems enhance drug solubility, optimize pharmacokinetics, and increase tumor accumulation while attenuating systemic toxicity.
  • Stimuli-responsive and multifunctional platforms improve precision targeting, although clinical adoption remains hindered by complex manufacturing, safety assessment challenges, and rigorous regulatory hurdles.

Cite This Study

Rehmani et al. (2026) studied this question.

synapsesocial.com/papers/6aabb6c75f706d05830e55a7https://doi.org/10.22270/jddt.v16i9.7989
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Nanocarrier-Based Strategies for Advanced Cancer Drug Delivery and Therapeutics: Design Principles, Biological Interactions, and Clinical Potential2026 · 12 citations
  2. 2Nanoparticles In Cancer Drug Delivery: Recent Advances, Therapeutic Applications And Challenges2026
  3. 3Nanocarrier Platforms in Cancer Therapeutics: Design, Advances and Clinical Translation Challenges2026
  4. 4A REVIEW ON RECENT ADVANCES IN NANOPARTICLE BASED DRUG DELIVERY SYSTEMS FOR CANCER THERAPY2026
  5. 5NANOCARRIER-BASED APPROACHES FOR ENHANCED ANTICANCER DRUG DELIVERY2026