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September 17, 2026Journal of Craniofacial Surgery

Management of Aplasia Cutis Congenita: An 11-Year Experience

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Authors

VMVamsi C. MohanWOWinston R. OwensAMAlexandra L McLennan

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Overview

Retrospective review reveals lesion size directs conservative versus surgical care in pediatric aplasia cutis congenita, suggesting surgery prevents severe complications.

Key Points

  • To examine clinical characteristics, comorbidity patterns, and management strategies for pediatric patients diagnosed with aplasia cutis congenita treated at an academic center.
  • Conducted a retrospective chart review of patients diagnosed with aplasia cutis congenita treated between January 2012 and October 2023 at a large academic pediatric hospital (N=144 with complete records analyzed out of 162 identified).
  • Among 144 patients, 55% (79/144) were female, 47% (67/144) had comorbidities, and 12% (17/144) presented with internal organ abnormalities, with an overall average lesion size of 7.05 cm² (range: 0.12–96 cm²).
  • Treatment modality stratified by lesion size: observation and education alone were used for lesions averaging 1.87 cm² (42%), local wound care for lesions averaging 7.14 cm² (21%), and surgical intervention for lesions averaging 16.19 cm² (range: 0.70–96 cm²; 26%), with 12% lost to follow-up.

Cite This Study

Mohan et al. (2026) studied this question.

synapsesocial.com/papers/6aabb6c75f706d05830e55cahttps://doi.org/10.1097/scs.0000000000013377
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Non-surgical management of severe aplasia cutis congenital accompanied by a bone defect – a case study2024
  2. 2A Closer Look at Aplasia Cutis Congenita: Understanding a Unique Case2024 · 1 citations
  3. 3Surgical management of aplasia cutis congenita of the scalp and skull defect in a resource-limited setting: A case report2026
  4. 4Clinical Characteristics, Management, and Prognosis of Newborns with Aplasia Cutis Congenita Type I: A Systematic Review and Case Report2026
  5. 5An Extensive Case of Aplasia Cutis Congenita2024 · 2 citations