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Correspondence clarifies serological classification in autoimmune evaluation, highlighting that reported anti-Ro/SSA measurements specifically reflect anti-Ro60 rather than anti-Ro52 reactivity.
We thank Dr. Lee1 for the interest in our published article2 and the valuable comments regarding the distinction between anti-Ro52/TRIM21 and anti-Ro60/TROVE2 antibodies within the Ro/SSA autoantibody system. We wish to clarify that in our study,2 the serological marker designated as "anti-Ro/SSA" specifically denotes anti-Ro60 antibodies rather than a composite measure of both anti-Ro52 and anti-Ro60.
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Wei et al. (2026) studied this question.
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