What question did this study set out to answer?

To evaluate 2-year clinical outcomes and whole blood metal ion levels following total hip arthroplasty using the Trinity modular dual-mobility prosthesis.

September 17, 2026Hip International

Total hip arthroplasty with dual-mobility components is associated with excellent clinical outcomes and low metal ion blood levels at 2 years

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Authors

KSKaran Sandhu LSLucy J. SalmonThe University of Sydney MLMatthew C. LyonsNorth Sydney Orthopaedic and Sports Medicine Centre

Discussion

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Implication

Clinical trial demonstrates high patient satisfaction and minimal metal ion release in hip arthroplasty patients, indicating favorable short-term safety for dual-mobility implants.

Key Points

To evaluate 2-year clinical outcomes and whole blood metal ion levels following total hip arthroplasty using the Trinity modular dual-mobility prosthesis.
Conducted an interventional clinical trial (ANZCTR: ACTRN12622000003774) of 104 consecutive patients undergoing primary total hip arthroplasty with the Trinity dual-mobility system.
Evaluated patient-reported outcome measures, including the Oxford Hip Score, HOOS-JR, and satisfaction, at baseline and 2-year follow-up (completed by n=101).
Measured whole blood levels of cobalt, chromium, and titanium at baseline (n=19) and at 2 years postoperatively (n=53).
At 2 years, 96% of patients were satisfied or very satisfied, with Patient Acceptable Symptom State thresholds attained by 85% for HOOS-JR and 87% for the Oxford Hip Score.
Mean blood levels from baseline to 2 years increased for titanium from 44 to 86 nmol/L (p=0.001), whereas changes for cobalt (6 to 8 nmol/L, p=0.348) and chromium (10 to 11 nmol/L, p=0.824) were not statistically significant.
Elevated concentrations (>1.0 µg/L) occurred in 7.5% of patients for cobalt and 1.8% for chromium, while titanium exceeded 5 µg/L in 17% (9/53), remaining far below levels indicative of severe prosthesis wear.

Cite This Study

Sandhu et al. (2026) studied this question.

synapsesocial.com/papers/6aabb75d5f706d05830e66ac https://doi.org/10.1177/11207000261474376

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Implication

Clinical trial demonstrates high patient satisfaction and minimal metal ion release in hip arthroplasty patients, indicating favorable short-term safety for dual-mobility implants.

Total hip arthroplasty with dual-mobility components is associated with excellent clinical outcomes and low metal ion blood levels at 2 years

Discussion

Member takes

Implication

Key Points

Cite This Study

Total hip arthroplasty with dual-mobility components is associated with excellent clinical outcomes and low metal ion blood levels at 2 years

Discussion

Member takes

Implication

Key Points

Cite This Study

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