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September 17, 2026International Journal of Behavioral Nutrition and Physical ActivityOpen Access

Intensity-specific physical activity and mortality in 147,414 adults: a pooled accelerometer analysis

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Authors

MSMichael J. SteinCLClaas LendtFBFabian Bamberg

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Overview

Prospective pooled cohort study reveals lower mortality across all exercise intensities in middle-aged and older adults, suggesting strong longevity benefits from brief vigorous activity.

Key Points

  • To examine the associations between light-, moderate-, and vigorous-intensity physical activity and mortality, and evaluate the effects of reallocating active time across intensities.
  • Prospective pooled analysis of device-measured physical activity among 147,414 participants aged 40–74 years from the German National Cohort (NAKO) and UK Biobank over a mean follow-up of 7.9 years.
  • Multivariable Cox proportional hazards models estimated hazard ratios (HRs) and 95% confidence intervals (CIs) for mortality across activity intensities and simulated time-reallocation models holding total active time constant.
  • During follow-up, 5,545 deaths occurred; 150 min/week of moderate-intensity activity was associated with lower mortality (HR: 0.70; 95% CI: 0.67, 0.72) compared with no activity, matching the risk reduction of ~510 min/week of light-intensity or ~12 min/week of vigorous-intensity activity.
  • Replacing 15 to 60 min/week of light- or moderate-intensity activity with vigorous-intensity activity was associated with an 18% to 30% further reduction in mortality risk.

Cite This Study

Stein et al. (2026) studied this question.

synapsesocial.com/papers/6aabb7755f706d05830e674bhttps://doi.org/10.1186/s12966-026-01980-3
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Also Consider

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  1. 1Even Low Levels of Physical Activity are Associated with Lower All-Cause Mortality: A Cohort Study of 594,000 US Adults2026
  2. 2Device-measured sedentary time and intensity-specific physical activity in relation to all-cause and cardiovascular disease mortality: the UK Biobank cohort study2024 · 27 citations
  3. 3Do Moderate‐Intensity and Vigorous‐Intensity Physical Activities Reduce Mortality Rates to the Same Extent?2014 · 117 citations
  4. 4Impact of Moderate-Intensity and Vigorous-Intensity Physical Activity on Mortality2017 · 69 citations
  5. 5JOINT EFFECT OF LIGHT AND MODERATE-TO-VIGOROUS PHYSICAL ACTIVITY ON LONGEVITY2026