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June 20, 2026Annals of EpidemiologyOpen Access

Even Low Levels of Physical Activity are Associated with Lower All-Cause Mortality: A Cohort Study of 594,000 US Adults

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Authors

APAdam W. PotterDLDavid P. LooneyWTWilliam J. Tharion

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Overview

Cohort study links higher physical activity to lower mortality risk in US adults, suggesting health benefits of even modest activity levels.

Key Points

  • This research aims to explore how varying levels of physical activity relate to all-cause mortality risk in a large sample of adults.
  • Analyzed data from 594,285 adults in the National Health Interview Survey from 1997-2018, linked to mortality data.
  • Moderate-to-vigorous physical activity was measured in minutes per week, including a true-zero category.
  • Used survey-weighted Cox proportional hazards models adjusted for various factors to estimate hazard ratios.
  • During a median follow-up of 9.5 years, there were 81,689 deaths observed.
  • Adjusted hazard ratios for mortality decreased from 0.87 at 5 minutes/week to 0.74 at 600 minutes/week of physical activity, compared to 0 minutes/week.
  • Ten-year mortality risk dropped significantly from 19.9% at 0 MVPA to 7.2% at over 600 minutes/week.

Cite This Study

Potter et al. (2026) studied this question.

synapsesocial.com/papers/6a362e62db0793dc1a536271https://doi.org/10.1016/j.annepidem.2026.110150
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Also Consider

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