Key result
Accelerometer-measured MVPA is linked to ~2% lower all-cause mortality starting from 10 minutes weekly.
Why the study?
The study was conducted to investigate the prospective dose-response association of accelerometer-measured moderate-to-vigorous physical activity with all-cause mortality and cardiovascular disease incidence.
Does accelerometer-measured moderate-to-vigorous physical activity reduce all-cause mortality and cardiovascular disease incidence in a general cohort?
Population
76,074 participants from the UK Biobank study
Comparison
Dose-response levels of moderate-to-vigorous physical activity
Design
Prospective cohort study
Follow-up
Median 8.0 years (IQR 7.5-8.5)
Authors
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Supports low MVPA thresholds observationally; leaves open causality and need for RCTs before practice change.
Cohort (n=76,074)
Does accelerometer-measured moderate-to-vigorous physical activity reduce all-cause mortality and cardiovascular disease incidence in a general cohort?
Hazard Ratio: 0.98 (95% CI 0.98–0.99)
As little as 10-15 minutes of moderate-to-vigorous physical activity per week reduces all-cause mortality and CVD incidence, with maximal efficiency between 100 and 250 minutes per week.
Polo‐López et al. (2024) reported a cohort. Moderate-to-vigorous physical activity (MVPA) was evaluated on All-cause mortality (HR 0.98, 95% CI 0.98-0.99). Accelerometer-measured moderate-to-vigorous physical activity was associated with reduced all-cause mortality (HR 0.98; 95% CI 0.98-0.99) starting from 10 minutes per week.
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