FasL-mediated death of activated intratumoral T cells drives secondary resistance to cancer immunotherapy

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1. 1The Treg-cell death axis in lung cancer: implications for immune evasion and novel therapeutic strategies2026
2. 2T _reg cells promote immunotherapy-induced immune evasion by restraining CD4 T cell control of MHC-I–deficient metastatic pancreatic cancer2026
3. 3Tumor-targeted therapy with BRAF-inhibitor recruits activated dendritic cells to promote tumor immunity in melanoma2024 · 10 citations
4. 4CD8+ T cell-derived Fgl2 regulates immunity in a cell-autonomous manner via ligation of FcγRIIB2024 · 5 citations
5. 5A Glucocorticoid-Fas axis controls immune evasion from pan-cytotoxic lymphocytes during metastatic seeding 23341932026