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September 17, 2026JMIR Public Health and SurveillanceOpen Access

Impact of a Culturally Tailored Educational Intervention on Human Papillomavirus Knowledge and Vaccination Intentions Among Women in Saudi Arabia: Quasi-Experimental Study

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Authors

EEEbtesam A. ElsayedFMFathia Ahmed MersalHMHeba Ahmed Osman Mohamed

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Overview

Quasi-experimental study demonstrates improved HPV knowledge and vaccination intentions in women, suggesting culturally adapted education overcomes vaccine hesitancy.

Key Points

  • To evaluate the impact of a culturally tailored educational intervention on HPV-related knowledge, health awareness, attitudes, and vaccination intentions among women in Northern Saudi Arabia.
  • Conducted a quasi-experimental pretest-posttest study with a control group among 380 women (190 intervention, 190 control) at primary health care centers in the Northern Border Region of Saudi Arabia.
  • Delivered a culturally adapted, 45-minute interactive group session to the intervention group, evaluating outcomes at baseline, 1-week post intervention, and 3-month follow-up.
  • At 3-month follow-up, the intervention group showed significant improvements in vaccination intentions (adjusted β=0.86, 95% CI 0.60-1.12; P<.001; Cohen d=0.82) compared with controls.
  • Intervention participants demonstrated significant gains in HPV knowledge (β=0.84, 95% CI 0.53-1.15; P<.001; d=0.45), health awareness (β=0.88, 95% CI 0.53-1.23; P<.001; d=0.44), and attitudes (β=0.70, 95% CI 0.42-0.98; P<.001; d=0.38).
  • Intervention effects remained consistent across demographic subgroups, showing no significant effect modification by age, education level, or health literacy (all interaction P>.10).

Cite This Study

Elsayed et al. (2026) studied this question.

synapsesocial.com/papers/6aabb8245f706d05830e7adehttps://doi.org/10.2196/104529
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