Coronary revascularization after surgical aortic valve replacement

Figures

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  Competing risk cumulative incidences of mortality and revascularization; 20-year follow-up.

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  Figure 1. Flowchart of patient inclusion. A total of 4228 patients underwent SAVR at the Erasmus MC between 1987 and 2015, of whom a total of 420 patients were eligible for the study. SAVR, Surgical aortic valve replacement.

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  Figure 2. Mortality and coronary revascularization after SAVR. Competing risk cumulative incidences of mortality and coronary revascularization during 20-year follow-up according to (A) blue line presents the cumulative incidence of all-cause mortality competing with the risk of revascularization in our cohort and (B) red line presents the cumulative incidence of revascularization with either PCI or CABG competing with the risk of revascularization in our cohort. SAVR, Surgical aortic valve replacement; PCI, percutaneous coronary intervention; CABG, coronary artery bypass grafting.

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  Figure 3. Revascularization after SAVR in various patient subgroups. Competing risk cumulative incidences of revascularization after SAVR in subgroups according to the following: (A) with and without previous revascularization. Blue line shows patients with no history of revascularization. Red line shows patients with a history of revascularization. (B) Age at SAVR younger or older than 65 years. Blue line shows patients aged 65 or older. Red line shows patients aged younger than 65 years. (C) With and without a history of hypercholesterolemia. Blue line shows patients with history of hypercholesterolemia. Red line shows patients without a history of hypercholesterolemia.

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  Figure 4. Revascularization after SAVR in various patient subgroups. Competing risk cumulative incidences of revascularization after SAVR in subgroups according to the following: (A) with and without a history of diabetes mellitus. Blue line shows patients with history of diabetes mellitus. Red line shows patients without a history of diabetes mellitus. (B) Primary indication for SAVR. Blue line shows patients undergoing SAVR for AS. Red line shows patients undergoing SAVR for AR. Green line shows patients undergoing SAVR for combined AS and AR. (C) Mechanical or biological prosthesis received. Blue line shows the use of a biological valve. Red line shows the use of a mechanical valve. AS, Aortic valve stenosis; AR, aortic regurgitation.

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  Figure 5. Cumulative competing risk incidence of revascularization presented as a graphical abstract. Competing risk cumulative incidence of coronary revascularization during 20-year after surgical aortic valve replacement. Coronary revascularization either done with coronary artery bypass grafting or percutaneous coronary intervention. Percutaneous coronary intervention is encircled. SAVR, Surgical aortic valve replacement; TAVR, transcatheter aortic valve replacement.