Acute Alveolar Hemorrhage in Lupus Erythematosus

Letters1 December 1975Acute Alveolar Hemorrhage in Lupus ErythematosusDANIEL B. GOULD, M.D., RAYMOND Z. SORIANO, M.D.DANIEL B. GOULD, M.D.Search for more papers by this author, RAYMOND Z. SORIANO, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-83-6-836 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptAcute pulmonary hemorrhage is a clinical complication of systemic lupus erythematosus rarely described. One report has described the case of a man who presented with hemoptysis as the initial manifestation and died of uncontrollable hemoptysis after 5 months; electron microscopic study of his lung biopsy showed electron-dense intramembranous deposits within alveolar capillary basement membranes (1). Another case study concerned a woman whose 20-month course of lupus erythematosus began with dyspnea; massive pulmonary hemosiderosis was the main autopsy finding (2). Lupus erythematosus has also been reported in association with diffuse pulmonary hemorrhage fatal in 9 days (3).The patient we describe...References1. KUHN C: Systemic lupus erythematosus in a patient with ultrastructural lesions of the pulmonary capillaries previously reported in the Review as due to idiopathic pulmonary hemosiderosis. Am Rev Resp Dis 106:931-932, 1972 CrossrefMedlineGoogle Scholar2. SIEGENTHALERHEDINGER RC: Massive Lungenhämosiderose bei Lupus erythematodes disseminatus. Schweiz Med Wochenschr 96:1323-1331, 1966 MedlineGoogle Scholar3. CLINICOPATHOLOGIC CONFERENCE: Proliferative glomerulonephritis and pulmonary hemorrhage. Am J Med 55:199-210, 1973 CrossrefMedlineGoogle Scholar4. BRENTJENSO'CONNELLPAWLOWSKI JDI: Experimental immune complex disease of lung. The pathogenesis of a laboratory model resembling certain human interstitial lung disease. J Exp Med 140:105-125, 1974 CrossrefMedlineGoogle Scholar5. HYATTADELSTEINHALAZUN REJ: Ultrastructure of the lung in idiopathic pulmonary hemosiderosis. Am J Med 52:822-829, 1972 CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. 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BORDER, M.D., RICHARD W. BAEHLER, M.D., DINYAR BHATHENA, M.D., RICHARD J. GLASSOCK, M.D.Immunopathologic Studies of Pneumonitis in Systemic Lupus ErythematosusTAKATOSHl INOUE, M.D., YOSHIHARU KANAYAMA, M.D., AKIKO OHE, M.D., NORIYUKI KATO, M.D., TETSUO HORIGUCHI, M.D., MASAMITSU ISHII, M.D., KENZO SHIOTA, M.D.The composition of pulmonary immune deposits in systemic lupus erythematosusDisseminated immune deposits in lupus erythematosusOccult Pulmonary HemorrhageABRAHAM ARONOW, M.D., GARY G. KARDOS, M.D. 1 December 1975Volume 83, Issue 6Page: 836-837KeywordsAutopsyBasement membraneBiopsyCapillariesDyspneaElectron microscopyHemorrhageLungsLupus erythematosus Issue Published: 1 December 1975 PDF downloadLoading ...