Key result
Borna disease virus p16 acts as a nonglycosylated matrix protein at the inner viral membrane.
Why the study?
Previous publications described the BDV p16 protein as N-glycosylated despite lacking consensus sequences for N glycosylation, creating uncertainty about its glycosylation and membrane topology.
Contrary to previous reports, the BDV p16 protein is a typical nonglycosylated matrix protein associated at the inner surface of the viral membrane.
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Reclassifies BDV p16 as nonglycosylated matrix protein; challenges prior reports and leaves open functional roles in assembly.
Kraus et al. (2001) studied Borna disease virus (BDV) infection. The Borna disease virus p16 protein is a typical nonglycosylated matrix protein associated at the inner surface of the viral membrane, rather than an N-glycosylated integral membrane protein.
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