Key result
Psychological distress linked to ~61% higher 5-year CHD risk in men, but not women.
Why the study?
The study aimed to confirm the association between psychological distress and coronary heart disease and to examine if this association is explained by existing physical illness.
Does psychological distress increase the risk of coronary heart disease in adults aged 45-64 years?
Population
6575 men and women aged 45-64 years from Paisley, Scotland
Comparison
Psychological distress vs no psychological distress
Design
Prospective cohort study with proportional hazards modelling
Authors
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Does not support incorporating distress into CHD risk assessment; leaves open sex-specific effects for prospective confirmation.
Cohort (n=6,575)
Yes
Does psychological distress increase the risk of coronary heart disease in adults aged 45-64 years?
Hazard Ratio: 1.61 (95% CI 1.02–2.55)
Psychological distress is associated with an increased 5-year risk of coronary heart disease in men, which is particularly pronounced in those with existing physical illness.
Farhat Rasul (2005) conducted a cohort in Coronary heart disease (CHD) (n=6,575). Psychological distress vs. No psychological distress was evaluated on Hospital admissions for CHD at 5 years (HR 1.61, 95% CI 1.02-2.55). Psychological distress was associated with an increased 5-year risk of coronary heart disease in men (HR 1.61; 95% CI 1.02-2.55) after adjusting for existing illness, but was unrelated to CHD in women.
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