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February 5, 2023Journal of Clinical MedicineOpen Access

Near-Infrared Spectroscopy Demonstrates the Benefit of Erythracytapheresis in Sickle Cell Disease Adult Patients with Cerebral Vasculopathy

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Authors

SMSuella MartinoUniversité Paris-Est Créteil RTRym Chouk TurkiÉtablissement Français du Sang FZFouzia ZouitiÉtablissement Français du Sang

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Implication

Prospective study reveals increased cerebral oxygenation during erythracytapheresis in adults with sickle cell disease, indicating improved brain perfusion in steno-occlusive vasculopathy.

Key Points

To assess real-time cerebral perfusion using near-infrared spectroscopy during erythracytapheresis in adults with sickle cell disease with and without cerebral steno-occlusive arterial disease.
Monocentric, prospective study conducted in 2014 evaluating 16 adult patients with sickle cell disease (10 with steno-occlusive arterial disease) undergoing erythracytapheresis.
Near-infrared spectroscopy continuously recorded relative concentrations of oxyhemoglobin, deoxyhemoglobin, and total hemoglobin in cerebral tissue and muscle during exchange transfusion.
Cerebral hemispheres affected by steno-occlusive arterial disease showed a statistically significant increase in oxyhemoglobin and total hemoglobin during exchange transfusion.
Deoxyhemoglobin concentrations showed no significant change in monitored cerebral regions during the procedure.

Cite This Study

Martino et al. (2023) studied this question.

synapsesocial.com/papers/6aabc144355ff47e9051f0a7 https://doi.org/10.3390/jcm12041256

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Implication

Prospective study reveals increased cerebral oxygenation during erythracytapheresis in adults with sickle cell disease, indicating improved brain perfusion in steno-occlusive vasculopathy.

Near-Infrared Spectroscopy Demonstrates the Benefit of Erythracytapheresis in Sickle Cell Disease Adult Patients with Cerebral Vasculopathy

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Implication

Key Points

Cite This Study

Near-Infrared Spectroscopy Demonstrates the Benefit of Erythracytapheresis in Sickle Cell Disease Adult Patients with Cerebral Vasculopathy

Discussion

Member takes

Implication

Key Points

Cite This Study

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