Key result
Shoulder disarticulation and adjuvant therapy yields 1-year recurrence-free survival in a secondary angiosarcoma case.
Why the study?
Angiosarcoma secondary to post-irradiation and chronic lymphedema is rare and aggressive with poor prognosis, requiring better understanding of clinical features to distinguish it from benign or other malignant diseases.
Design
Case report
Follow-up
1 year (for one patient)
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May support aggressive resection plus adjuvant therapy in select cases; leaves open validation in larger prospective cohorts.
Case Report (n=3)
In patients with a history of irradiation and chronic lymphedema presenting with suspicious skin lesions, prompt biopsy is essential to diagnose aggressive secondary angiosarcoma.
A 2021 study conducted a case report in Angiosarcoma secondary to post-irradiation and chronic lymphedema (n=3). Post-irradiation and chronic lymphedema was evaluated on Recurrence. Among three patients with angiosarcoma secondary to post-irradiation and chronic lymphedema, one treated with shoulder disarticulation and adjuvant therapy remained recurrence-free for 1 year.
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