Key result
AV delay optimization during exercise linked to ~19% higher cardiac output in CRT patients.
Why the study?
There are limited data on the impact of exercise-induced changes in heart rate on the optimal atrioventricular delay and left ventricular function in CRT recipients.
Does optimisation of atrioventricular delay during exercise improve cardiac output in patients with cardiac resynchronisation therapy?
Does optimisation of atrioventricular delay during exercise improve cardiac output in patients with cardiac resynchronisation therapy?
Absolute Event Rate: 6.2% vs 5.2%
p-value: p=<0.001
Optimising AV delay during exercise significantly improves cardiac output in CRT patients, supporting the use of rate-adaptive AV delay programming.
No takes yet. Share an insight, caveat, or question.
May support rate-adaptive AV delay in CRT; hypothesis-generating, needs randomized confirmation before practice change.
Sun et al. (2011) studied Cardiac resynchronisation therapy (n=97). AV delay optimisation vs. Without optimisation was evaluated on Cardiac output during stage I exercise (p=<0.001). AV delay optimisation during exercise significantly improved cardiac output compared to no optimisation in CRT patients during stage I (6.2 vs 5.2 l/min, p<0.001) and stage II exercise.
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