Key result
Point-of-care D-dimer testing for suspected DVT saves ~€103 per patient vs lab testing with similar outcomes.
Why the study?
The cost-effectiveness of point-of-care-test D-dimer assays compared to regular laboratory-based assays in the diagnostic work-up of DVT was unknown.
Does a point-of-care D-dimer testing strategy improve cost-effectiveness compared to laboratory-based testing for excluding DVT in general practice?
Population
Simulated patients presenting with symptoms of DVT at the general practitioner
Comparison
POCT D-dimer at phlebotomy service or GP practice vs regular laboratory-based D-dimer strategy
Design
Patient-level simulation model using literature-based probabilities, costs, and outcomes
Follow-up
6 months
Authors
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May support cost-saving DVT evaluation in primary care; leaves open prospective confirmation of outcome equivalence.
Does a point-of-care D-dimer testing strategy improve cost-effectiveness compared to laboratory-based testing for excluding DVT in general practice?
Effect estimate: €103 cost-savings (95% CI -117 to 89)
Absolute Event Rate: 724% vs 827%
Point-of-care D-dimer testing for DVT exclusion in primary care is cost-saving and yields similar health outcomes compared to standard laboratory testing.
Heerink et al. (2023) studied Suspected deep vein thrombosis (n=10,000). Point-of-care D-dimer testing (DVT care pathway) vs. Regular strategy (laboratory-based D-dimer assay) was evaluated on Cost-savings per patient (€103 cost-savings, 95% CI -117 to 89). Point-of-care D-dimer testing for suspected deep vein thrombosis yielded similar health outcomes but saved €87 to €103 per patient compared to the regular laboratory-based strategy.
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