Key result
Anticoagulation and prednisone resolve features suggesting HOCM in a patient with eosinophilic heart disease.
Why the study?
Eosinophilic heart disease can present with clinical and imaging features mimicking hypertrophic obstructive cardiomyopathy, complicating diagnosis and management.
Eosinophilic heart disease can present with features mimicking hypertrophic obstructive cardiomyopathy, which may resolve with appropriate medical therapy including anticoagulation and prednisone.
Eosinophilic disease may mimic reversible HOCM; leaves open whether biopsy should guide therapy in atypical cases.
We report a 25-year-old female with characteristic features of eosinophilic heart disease on clinical presentation, echocardiography, cardiac catheterization, and LV endomyocardial biopsy. Concomitant physical examination and echocardiographic findings suggesting hypertrophic obstructive cardiomyopathy resolved during treatment with anticoagulation and prednisone therapy.
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Miller et al. (1987) studied this question. Anticoagulation and prednisone therapy resolved clinical and echocardiographic features suggesting hypertrophic obstructive cardiomyopathy in a patient with eosinophilic heart disease.
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